Anti-TERT Antibody
Boster Bio Anti-TERT Antibody catalog # A00012-3. Tested in WB, ELISA. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase. TERT plays a key role in cancer formation, ensuring chromosomal stability by maintaining telomere length, and allowing cells to avert senescence. It constitutes a limiting factor for formation of the telomerase complex in cancer cells. TERT is one of two major components of the larger telomerase complex, which extends telomeres by adding specific short repetitive DNA sequences. Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. The calculated MW of TERT is 127 kDa, 27586-1-AP can detect a band around 100 kDa.
Gene Name
TERT
UniProt
O14746
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human TERT recombinant protein (Position: G221-W317) .
Clonality
Polyclonal
Applications
WB, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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