Anti-DPH1 Antibody Picoband® APC Conjugated
Product Specifications
Background
The protein encoded by this gene is an enzyme involved in the biosynthesis of diphthamide, a modified histidine found only in elongation factor-2 (EEF2) . Diphthamide residues in EEF2 are targeted for ADP-ribosylation by diphtheria toxin and Pseudomonas exotoxin A. Defects in this gene have been associated with both ovarian cancer and autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies.
Synonyms
DPH1; DPH2L; DPH2L1; OVCA1; 2- (3-amino-3-carboxypropylhistidine synthase subunit 1; EC 2.5.1.108; Diphthamide biosynthesis protein 1; Diphtheria toxin resistance protein 1; Ovarian cancer-associated gene 1 protein; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1
Gene Name
DPH1
Gene ID
1801
UniProt
Q9BZG8
Host
Rabbit
Reactivity
Human, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human DPH1 recombinant protein (Position: P50-P438) .
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
48 kDa
Applications Notes
6
Gene Name Synonym
Diphthamide biosynthesis 1
Protein Name
2- (3-amino-3-carboxypropyl) histidine synthase subunit 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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