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Anti-DPH1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

The protein encoded by this gene is an enzyme involved in the biosynthesis of diphthamide, a modified histidine found only in elongation factor-2 (EEF2) . Diphthamide residues in EEF2 are targeted for ADP-ribosylation by diphtheria toxin and Pseudomonas exotoxin A. Defects in this gene have been associated with both ovarian cancer and autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies.

Synonyms

DPH1; DPH2L; DPH2L1; OVCA1; 2- (3-amino-3-carboxypropylhistidine synthase subunit 1; EC 2.5.1.108; Diphthamide biosynthesis protein 1; Diphtheria toxin resistance protein 1; Ovarian cancer-associated gene 1 protein; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1

Gene Name

DPH1

Gene ID

1801

UniProt

Q9BZG8

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human DPH1 recombinant protein (Position: P50-P438) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

48 kDa

Applications Notes

6

Gene Name Synonym

Diphthamide biosynthesis 1

Protein Name

2- (3-amino-3-carboxypropyl) histidine synthase subunit 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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