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Anti-GSDME Antibody Picoband® APC Conjugated

Product Specifications

Background

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms

GSDME; DFNA5; ICERE1; Gasdermin-E; Inversely correlated with estrogen receptor expression 1; ICERE-1; Non-syndromic hearing impairment protein 5 [Cleaved into: Gasdermin-E, N-terminal; GSDME-NT; Gasdermin-E, C-terminal; GSDME-CT]

Gene Name

GSDME

Gene ID

1687

UniProt

O60443

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human GSDME recombinant protein (Position: M1-K475) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

55 kDa

Applications Notes

6

Gene Name Synonym

Gasdermin E

Protein Name

Gasdermin-E

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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