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Anti-DGUOK Antibody Picoband® FITC Conjugated

Product Specifications

Background

In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Synonyms

DGUOK; DGK; Deoxyguanosine kinase, mitochondrial; dGK; EC 2.7.1.113

Gene Name

DGUOK

Gene ID

1716

UniProt

Q16854

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human DGUOK recombinant protein (Position: Q76-L277) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

32 kDa

Applications Notes

6

Gene Name Synonym

Deoxyguanosine kinase

Protein Name

Deoxyguanosine kinase, mitochondrial

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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