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Anti-PURA Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Synonyms

PURA; PUR1; Transcriptional activator protein Pur-alpha; Purine-rich single-stranded DNA-binding protein alpha

Gene Name

PURA

Gene ID

5813

UniProt

Q00577

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human PURA.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

35 kDa

Applications Notes

6

Gene Name Synonym

Purine rich element binding protein A

Protein Name

Transcriptional activator protein Pur-alpha

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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