Anti-SCN4A Antibody Picoband® Fluoro488 Conjugated

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders.

SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4

E.coli-derived human SCN4A recombinant protein (Position: E35-S1788) . Human SCN4A shares 93.8% and 94% amino acid (aa) sequence identity with mouse and rat SCN4A, respectively.