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Anti-TBX5 Antibody Picoband® APC Conjugated

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Synonyms

TBX5; T-box transcription factor TBX5; T-box protein 5

Gene Name

TBX5

Gene ID

6910

UniProt

Q99593

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TBX5 recombinant protein (Position: K253-S518) . Human TBX5 shares 94.7% and 94.4% amino acid (aa) sequence identity with mouse and rat TBX5, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

58 kDa

Applications Notes

6

Gene Name Synonym

T-box transcription factor 5

Protein Name

T-box transcription factor TBX5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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