Anti-TBX5 Antibody Picoband® Cy3 Conjugated

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

E.coli-derived human TBX5 recombinant protein (Position: K253-S518) . Human TBX5 shares 94.7% and 94.4% amino acid (aa) sequence identity with mouse and rat TBX5, respectively.