Anti-DUSP2 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.
Synonyms
DUSP2; PAC1; Dual specificity protein phosphatase 2; EC 3.1.3.16; EC 3.1.3.48; Dual specificity protein phosphatase PAC-1
Gene Name
DUSP2
Gene ID
1844
UniProt
Q05923
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human DUSP2 recombinant protein (Position: M1-G250) . Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
34 kDa
Gene Name Synonym
Dual specificity phosphatase 2
Protein Name
Dual specificity protein phosphatase 2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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