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Anti-PDE4A Antibody FITC Conjugated

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms

PDE4A; DPDE2; cAMP-specific 3',5'-cyclic phosphodiesterase 4A; EC 3.1.4.53; DPDE2; PDE46

Gene Name

PDE4A

Gene ID

5141

UniProt

P27815

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human PDE4A. Human PDE4A shares 100% amino acid (aa) sequence identity with both mouse and rat PDE4A.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Phosphodiesterase 4A

Protein Name

3',5'-cyclic-AMP phosphodiesterase 4A

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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