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Anti-TTL Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529) . Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]) .

Synonyms

TTL; Tubulin--tyrosine ligase; TTL; EC 6.3.2.25

Gene Name

TTL

Gene ID

150465

UniProt

Q8NG68

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TTL recombinant protein (Position: N104-L377) . Human TTL shares 95.3% and 95.6% amino acid (aa) sequence identity with mouse and rat TTL, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

43 kDa

Applications Notes

6

Gene Name Synonym

Tubulin tyrosine ligase

Protein Name

Tubulin--tyrosine ligase

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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