Anti-TTL Antibody Picoband® Biotin Conjugated
Product Specifications
Background
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529) . Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]) .
Synonyms
TTL; Tubulin--tyrosine ligase; TTL; EC 6.3.2.25
Gene Name
TTL
Gene ID
150465
UniProt
Q8NG68
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TTL recombinant protein (Position: N104-L377) . Human TTL shares 95.3% and 95.6% amino acid (aa) sequence identity with mouse and rat TTL, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
43 kDa
Gene Name Synonym
Tubulin tyrosine ligase
Protein Name
Tubulin--tyrosine ligase
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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