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Anti-TIGAR Antibody Picoband® APC Conjugated

Product Specifications

Background

Enables fructose-2,6-bisphosphate 2-phosphatase activity. Involved in positive regulation of pentose-phosphate shunt and response to ischemia. Acts upstream of or within several processes, including fructose 2,6-bisphosphate metabolic process; negative regulation of catabolic process; and positive regulation of cardiac muscle cell apoptotic process. Located in mitochondrion. Is expressed in several structures, including brain; heart; immune system; and liver. Orthologous to human TIGAR (TP53 induced glycolysis regulatory phosphatase) .

Synonyms

Tigar; Fructose-2,6-bisphosphatase TIGAR; EC 3.1.3.46; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase

Gene Name

TIGAR

Gene ID

319801

UniProt

Q8BZA9

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse TIGAR recombinant protein (Position: M1-H269) . Mouse TIGAR shares 72.8% amino acid (aa) sequence identity with human TIGAR.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

30 kDa

Applications Notes

6

Gene Name Synonym

Trp53 induced glycolysis regulatory phosphatase

Protein Name

Fructose-2,6-bisphosphatase TIGAR

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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