Anti-UBE4B Antibody Picoband® Biotin Conjugated
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms
UBE4B; HDNB1; KIAA0684; UFD2; Ubiquitin conjugation factor E4 B; EC 2.3.2.27; Homozygously deleted in neuroblastoma 1; RING-type E3 ubiquitin transferase E4 B; Ubiquitin fusion degradation protein 2
Gene Name
UBE4B
Gene ID
10277
UniProt
O95155
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human UBE4B recombinant protein (Position: S184-H1302) .
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
146 kDa
Gene Name Synonym
Ubiquitination factor E4B
Protein Name
Ubiquitin conjugation factor E4 B
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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