Anti-TMP21/TMED10 Antibody Picoband® Fluoro488 Conjugated

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

TMED10; TMP21; Transmembrane emp24 domain-containing protein 10; 21 kDa transmembrane-trafficking protein; S31III125; S31I125; Tmp-21-I; Transmembrane protein Tmp21; p23; p24 family protein delta-1; p24delta1; p24delta

E.coli-derived human TMP21/TMED10 recombinant protein (Position: R27-M194) . Human TMP21/TMED10 shares 97% amino acid (aa) sequence identity with both mouse and rat TMP21/TMED10.