Anti-TRAF3IP2 Antibody Picoband® PE Conjugated
Product Specifications
Background
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Synonyms
TRAF3IP2; C6orf2; C6orf4; C6orf5; C6orf6; Adapter protein CIKS; Connection to IKK and SAPK/JNK; Nuclear factor NF-kappa-B activator 1; ACT1; TRAF3-interacting protein 2
Gene Name
TRAF3IP2
Gene ID
10758
UniProt
O43734
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TRAF3IP2 recombinant protein (Position: M1-H528) . Human TRAF3IP2 shares 77% amino acid (aa) sequence identity with mouse TRAF3IP2.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
65 kDa
Applications Notes
6
Gene Name Synonym
TRAF3 interacting protein 2
Protein Name
E3 ubiquitin ligase TRAF3IP2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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