Anti-TOP1MT Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
TOP1MT; DNA topoisomerase I, mitochondrial; TOP1mt; EC 5.6.2.1
Gene Name
TOP1MT
Gene ID
116447
UniProt
Q969P6
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TOP1MT recombinant protein (Position: E18-F601) .
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
70 kDa
Applications Notes
6
Gene Name Synonym
DNA topoisomerase I mitochondrial
Protein Name
DNA topoisomerase I, mitochondrial
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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