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Anti-TPCN2 Antibody Picoband® HRP Conjugated

Product Specifications

Background

This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.

Synonyms

TPCN2; TPC2; Two pore calcium channel protein 2; Voltage-dependent calcium channel protein TPC2

Gene Name

TPCN2

Gene ID

219931

UniProt

Q8NHX9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TPCN2 recombinant protein (Position: L26-R752) . Human TPCN2 shares 74.9% amino acid (aa) sequence identity with mouse TPCN2.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

85 kDa

Gene Name Synonym

Two pore segment channel 2

Protein Name

Two pore channel protein 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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