Anti-TPCN2 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.
Synonyms
TPCN2; TPC2; Two pore calcium channel protein 2; Voltage-dependent calcium channel protein TPC2
Gene Name
TPCN2
Gene ID
219931
UniProt
Q8NHX9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TPCN2 recombinant protein (Position: L26-R752) . Human TPCN2 shares 74.9% amino acid (aa) sequence identity with mouse TPCN2.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
85 kDa
Gene Name Synonym
Two pore segment channel 2
Protein Name
Two pore channel protein 2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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