Anti-TPBG Antibody Picoband® FITC Conjugated

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

TPBG; 5T4; Trophoblast glycoprotein; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; M6P1; Wnt-activated inhibitory factor 1; WAIF1

E.coli-derived human TPBG recombinant protein (Position: E70-V420) . Human TPBG shares 84.3% and 83.5% amino acid (aa) sequence identity with mouse and rat TPBG, respectively.