Anti-PARL Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
Synonyms
PARL; PSARL; PRO2207; Presenilins-associated rhomboid-like protein, mitochondrial; EC 3.4.21.105; Mitochondrial intramembrane cleaving protease PARL [Cleaved into: P-beta; Pbeta]
Gene Name
PARL
Gene ID
55486
UniProt
Q9H300
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human PARL. Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse and rat PARL.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
43 kDa
Applications Notes
6
Gene Name Synonym
Presenilin associated rhomboid like
Protein Name
Presenilin-associated rhomboid-like protein, mitochondrial
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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