Anti-LAP2/TMPO Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription.
Synonyms
TMPO; LAP2; Lamina-associated polypeptide 2, isoform alpha; Thymopoietin isoform alpha; TP alpha; Thymopoietin-related peptide isoform alpha; TPRP isoform alpha [Cleaved into: Thymopoietin; TP; Splenin; Thymopentin; TP5]
Gene Name
TMPO
Gene ID
7112
UniProt
P42166
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human LAP2/TMPO recombinant protein (Position: N24-P672) . Human LAP2/TMPO shares 78.8% amino acid (aa) sequence identity with mouse LAP2/TMPO.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
75 kDa
Applications Notes
6
Gene Name Synonym
Thymopoietin
Protein Name
Lamina-associated polypeptide 2, isoform alpha
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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