Anti-TDO2 Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.
Synonyms
TDO2; TDO; Tryptophan 2,3-dioxygenase; TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase
Gene Name
TDO2
Gene ID
6999
UniProt
P48775
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TDO2 recombinant protein (Position: K16-D406) . Human TDO2 shares 89.3% amino acid (aa) sequence identity with both mouse and rat TDO2.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
48 kDa
Applications Notes
6
Gene Name Synonym
Tryptophan 2,3-dioxygenase
Protein Name
Tryptophan 2,3-dioxygenase
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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