Anti-TDO2 Antibody Picoband® HRP Conjugated

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

TDO2; TDO; Tryptophan 2,3-dioxygenase; TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase

E.coli-derived human TDO2 recombinant protein (Position: K16-D406) . Human TDO2 shares 89.3% amino acid (aa) sequence identity with both mouse and rat TDO2.