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Anti-TDO2 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Synonyms

TDO2; TDO; Tryptophan 2,3-dioxygenase; TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase

Gene Name

TDO2

Gene ID

6999

UniProt

P48775

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TDO2 recombinant protein (Position: K16-D406) . Human TDO2 shares 89.3% amino acid (aa) sequence identity with both mouse and rat TDO2.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

48 kDa

Applications Notes

6

Gene Name Synonym

Tryptophan 2,3-dioxygenase

Protein Name

Tryptophan 2,3-dioxygenase

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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