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Anti-TCIRG1 Antibody Fluoro647 Conjugated

Product Specifications

Background

This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase) . The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

Synonyms

TCIRG1; ATP6N1C; ATP6V0A3; V-type proton ATPase 116 kDa subunit a isoform 3; V-ATPase 116 kDa isoform a3; Osteoclastic proton pump 116 kDa subunit; OC-116 kDa; OC116; T-cell immune regulator 1; T-cell immune response cDNA7 protein; TIRC7; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3

Gene Name

TCIRG1

Gene ID

10312

UniProt

Q13488

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TCIRG1 recombinant protein (Position: Q48-D680) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

T cell immune regulator 1, ATPase H+ transporting V0 subunit a3

Protein Name

V-type proton ATPase 116 kDa subunit a 3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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