Anti-TCIRG1 Antibody APC Conjugated

This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase) . The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

TCIRG1; ATP6N1C; ATP6V0A3; V-type proton ATPase 116 kDa subunit a isoform 3; V-ATPase 116 kDa isoform a3; Osteoclastic proton pump 116 kDa subunit; OC-116 kDa; OC116; T-cell immune regulator 1; T-cell immune response cDNA7 protein; TIRC7; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3