Anti-TCIRG1 Antibody Biotin Conjugated
Product Specifications
Background
This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase) . The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.
Synonyms
TCIRG1; ATP6N1C; ATP6V0A3; V-type proton ATPase 116 kDa subunit a isoform 3; V-ATPase 116 kDa isoform a3; Osteoclastic proton pump 116 kDa subunit; OC-116 kDa; OC116; T-cell immune regulator 1; T-cell immune response cDNA7 protein; TIRC7; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3
Gene Name
TCIRG1
Gene ID
10312
UniProt
Q13488
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TCIRG1 recombinant protein (Position: Q48-D680) .
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Gene Name Synonym
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
Protein Name
V-type proton ATPase 116 kDa subunit a 3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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