Anti-REST Antibody Picoband® FITC Conjugated
Product Specifications
Background
This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described.
Synonyms
REST; NRSF; XBR; RE1-silencing transcription factor; Neural-restrictive silencer factor; X2 box repressor
Gene Name
REST
Gene ID
5978
UniProt
Q13127
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human REST recombinant protein (Position: E110-E1097) . Human REST shares 62.9% and 59.6% amino acid (aa) sequence identity with mouse and rat REST, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
122 kDa
Applications Notes
6
Gene Name Synonym
RE1 silencing transcription factor
Protein Name
RE1-silencing transcription factor
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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