Anti-TMEM173/STING Antibody Picoband® Fluoro488 Conjugated

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

TMEM173; ERIS; MITA; STING; Stimulator of interferon genes protein; hSTING; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173

E.coli-derived human TMEM173/STING recombinant protein (Position: L66-K347) . Human TMEM173/STING shares 72.5% and 71.9% amino acid (aa) sequence identity with mouse and rat TMEM173/STING, respectively.