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Anti-BIGH3/TGFBI Antibody Picoband® Biotin Conjugated

Product Specifications

Background

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Synonyms

TGFBI; BIGH3; Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP

Gene Name

TGFBI

Gene ID

7045

UniProt

Q15582

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human BIGH3/TGFBI recombinant protein (Position: K27-H683) . Human BIGH3/TGFBI shares 91.2% amino acid (aa) sequence identity with mouse BIGH3/TGFBI.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

75 kDa

Gene Name Synonym

Transforming growth factor beta induced

Protein Name

Transforming growth factor-beta-induced protein ig-h3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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