Anti-SEC63 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Synonyms
SEC63; SEC63L; Translocation protein SEC63 homolog
Gene Name
SEC63
Gene ID
11231
UniProt
Q9UGP8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SEC63 recombinant protein (Position: R37-D760) . Human SEC63 shares 96.1% amino acid (aa) sequence identity with mouse SEC63.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
90 kDa
Applications Notes
6
Gene Name Synonym
SEC63 protein translocation regulator
Protein Name
Translocation protein SEC63 homolog
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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