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Anti-SEC63 Antibody Picoband® Biotin Conjugated

Product Specifications

Background

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Synonyms

SEC63; SEC63L; Translocation protein SEC63 homolog

Gene Name

SEC63

Gene ID

11231

UniProt

Q9UGP8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SEC63 recombinant protein (Position: R37-D760) . Human SEC63 shares 96.1% amino acid (aa) sequence identity with mouse SEC63.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

90 kDa

Gene Name Synonym

SEC63 protein translocation regulator

Protein Name

Translocation protein SEC63 homolog

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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