Anti-ZIP8/SLC39A8 Antibody Picoband® Fluoro488 Conjugated

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

SLC39A8; BIGM103; ZIP8; PP3105; Zinc transporter ZIP8; BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; LZT-Hs6; Solute carrier family 39 member 8; Zrt- and Irt-like protein 8; ZIP-8

E.coli-derived human ZIP8/SLC39A8 recombinant protein (Position: E23-A438) . Human ZIP8/SLC39A8 shares 89.5% and 87.8% amino acid (aa) sequence identity with mouse and rat ZIP8/SLC39A8, respectively.