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Anti-ZNT8/SLC30A Antibody HRP Conjugated

Product Specifications

Background

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8

Gene Name

SLC30A8

Gene ID

169026

UniProt

Q8IWU4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human ZNT8/SLC30A recombinant protein (Position: M1-C361) . Human ZNT8/SLC30A shares 80.6% and 78.1% amino acid (aa) sequence identity with mouse and rat ZNT8/SLC30A, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Gene Name Synonym

Solute carrier family 30 member 8

Protein Name

Proton-coupled zinc antiporter SLC30A8

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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