Anti-ZNT8/SLC30A Antibody FITC Conjugated
Product Specifications
Background
The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.
Synonyms
SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
Gene Name
SLC30A8
Gene ID
169026
UniProt
Q8IWU4
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human ZNT8/SLC30A recombinant protein (Position: M1-C361) . Human ZNT8/SLC30A shares 80.6% and 78.1% amino acid (aa) sequence identity with mouse and rat ZNT8/SLC30A, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Solute carrier family 30 member 8
Protein Name
Proton-coupled zinc antiporter SLC30A8
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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