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Anti-SPINK5 Antibody Picoband® HRP Conjugated

Product Specifications

Background

Enables peptidase inhibitor activity. Acts upstream of or within negative regulation of serine-type peptidase activity and regulation of cell adhesion. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; epidermal lamellar body; and perinuclear region of cytoplasm. Predicted to be active in extracellular region. Is expressed in back skin. Used to study Netherton syndrome. Human ortholog (s) of this gene implicated in Netherton syndrome. Orthologous to human SPINK5 (serine peptidase inhibitor Kazal type 5) .

Synonyms

SPINK5; Serine protease inhibitor Kazal-type 5; Lympho-epithelial Kazal-type-related inhibitor; LEKTI [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665]

Gene Name

SPINK5

Gene ID

72432

UniProt

Q5K5D4

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse SPINK5 recombinant protein (Position: H191-N506) . Mouse SPINK5 shares 59.8% amino acid (aa) sequence identity with human SPINK5.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

121 kDa

Gene Name Synonym

Serine peptidase inhibitor, Kazal type 5

Protein Name

Serine protease inhibitor Kazal-type 5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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