Anti-SPINK5 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables peptidase inhibitor activity. Acts upstream of or within negative regulation of serine-type peptidase activity and regulation of cell adhesion. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; epidermal lamellar body; and perinuclear region of cytoplasm. Predicted to be active in extracellular region. Is expressed in back skin. Used to study Netherton syndrome. Human ortholog (s) of this gene implicated in Netherton syndrome. Orthologous to human SPINK5 (serine peptidase inhibitor Kazal type 5) .
Synonyms
SPINK5; Serine protease inhibitor Kazal-type 5; Lympho-epithelial Kazal-type-related inhibitor; LEKTI [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665]
Gene Name
SPINK5
Gene ID
72432
UniProt
Q5K5D4
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived mouse SPINK5 recombinant protein (Position: H191-N506) . Mouse SPINK5 shares 59.8% amino acid (aa) sequence identity with human SPINK5.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
121 kDa
Gene Name Synonym
Serine peptidase inhibitor, Kazal type 5
Protein Name
Serine protease inhibitor Kazal-type 5
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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