Anti-P2RX1 Antibody Picoband® HRP Conjugated

The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis.

A synthetic peptide corresponding to a sequence in the middle region of human P2RX1. Human P2RX1 shares 80% and 75% amino acid (aa) sequence identity with mouse and rat P2RX1, respectively.