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Anti-MPEG1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Enables pore-forming activity and wide pore channel activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I; defense response to bacterium; and dendritic cell antigen processing and presentation. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent. Located in phagocytic vesicle. Is active in endolysosome and phagocytic vesicle membrane. Is expressed in several structures, including blood vessel; central nervous system; genital tubercle; and retina outer nuclear layer. Human ortholog (s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MPEG1 (macrophage expressed 1) .

Synonyms

Mpeg1; Macrophage-expressed gene 1 protein; Macrophage gene 1 protein; Mpg-1; Perforin-2; P-2; Protein MPS1

Gene Name

MPEG1

Gene ID

17476

UniProt

A1L314

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse MPEG1 recombinant protein (Position: F31-D645) . Mouse MPEG1 shares 79.4% and 93.5% amino acid (aa) sequence identity with human and rat MPEG1, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

79 kDa

Applications Notes

6

Gene Name Synonym

Macrophage expressed gene 1

Protein Name

Macrophage-expressed gene 1 protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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