Anti-MPEG1 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables pore-forming activity and wide pore channel activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I; defense response to bacterium; and dendritic cell antigen processing and presentation. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent. Located in phagocytic vesicle. Is active in endolysosome and phagocytic vesicle membrane. Is expressed in several structures, including blood vessel; central nervous system; genital tubercle; and retina outer nuclear layer. Human ortholog (s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MPEG1 (macrophage expressed 1) .
Synonyms
Mpeg1; Macrophage-expressed gene 1 protein; Macrophage gene 1 protein; Mpg-1; Perforin-2; P-2; Protein MPS1
Gene Name
MPEG1
Gene ID
17476
UniProt
A1L314
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived mouse MPEG1 recombinant protein (Position: F31-D645) . Mouse MPEG1 shares 79.4% and 93.5% amino acid (aa) sequence identity with human and rat MPEG1, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
79 kDa
Gene Name Synonym
Macrophage expressed gene 1
Protein Name
Macrophage-expressed gene 1 protein
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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