Anti-SMARCAL1 Antibody Picoband® Biotin Conjugated

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.

SMARCAL1; HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; EC 3.6.4.-; HepA-related protein; hHARP; Sucrose nonfermenting protein 2-like 1

E.coli-derived human SMARCAL1 recombinant protein (Position: M1-L782) . Human SMARCAL1 shares 70.8% and 72.6% amino acid (aa) sequence identity with mouse and rat SMARCAL1, respectively.