Anti-SETX Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Predicted to enable RNA binding activity; identical protein binding activity; and transcription termination site sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and termination of RNA polymerase II transcription. Predicted to be located in several cellular components, including growth cone; intercellular bridge; and nuclear lumen. Predicted to be active in nuclear body. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study amyotrophic lateral sclerosis type 4. Human ortholog (s) of this gene implicated in amyotrophic lateral sclerosis type 4 and spinocerebellar ataxia with axonal neuropathy 2. Orthologous to human SETX (senataxin) .
Synonyms
Setx; Als4; Kiaa0625; Probable helicase senataxin; EC 3.6.4.-; Amyotrophic lateral sclerosis 4 protein homolog; SEN1 homolog
Gene Name
SETX
Gene ID
269254
UniProt
A2AKX3
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived mouse SETX recombinant protein (Position: S28-R2447) . Mouse SETX shares 72.8% amino acid (aa) sequence identity with humanSETX.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
300 kDa
Gene Name Synonym
Senataxin
Protein Name
Probable helicase senataxin
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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