Anti-NCOR1 Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
Synonyms
NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1
Gene Name
NCOR1
Gene ID
9611
UniProt
O75376
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NCOR1 recombinant protein (Position: H23-Q2075) . Human NCOR1 shares 91.7% amino acid (aa) sequence identity with mouse NCOR1.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
300 kDa
Applications Notes
6
Gene Name Synonym
Nuclear receptor corepressor 1
Protein Name
Nuclear receptor corepressor 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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