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Anti-MTMR3 Antibody Picoband® APC Conjugated

Product Specifications

Background

This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol (3) -phosphate and phosphatidylinositol (3,5) -biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

MTMR3; KIAA0371; ZFYVE10; Myotubularin-related protein 3; EC 3.1.3.48; FYVE domain-containing dual specificity protein phosphatase 1; FYVE-DSP1; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; EC 3.1.3.95; Phosphatidylinositol-3-phosphate phosphatase; EC 3.1.3.64; Zinc finger FYVE domain-containing protein 10

Gene Name

MTMR3

Gene ID

8897

UniProt

Q13615

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human MTMR3 recombinant protein (Position: M1-E1074) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

134 kDa

Applications Notes

6

Gene Name Synonym

Myotubularin related protein 3

Protein Name

Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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