Anti-SETX Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4) .
Synonyms
SETX; ALS4; KIAA0625; SCAR1; Probable helicase senataxin; EC 3.6.4.-; Amyotrophic lateral sclerosis 4 protein; SEN1 homolog; Senataxin
Gene Name
SETX
Gene ID
23064
UniProt
Q7Z333
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SETX recombinant protein (Position: E29-R2544) . Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
303 kDa
Applications Notes
6
Gene Name Synonym
Senataxin
Protein Name
Probable helicase senataxin
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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