Anti-SETX Antibody Picoband® HRP Conjugated
Product Specifications
Background
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4) .
Synonyms
SETX; ALS4; KIAA0625; SCAR1; Probable helicase senataxin; EC 3.6.4.-; Amyotrophic lateral sclerosis 4 protein; SEN1 homolog; Senataxin
Gene Name
SETX
Gene ID
23064
UniProt
Q7Z333
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SETX recombinant protein (Position: E29-R2544) . Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
303 kDa
Gene Name Synonym
Senataxin
Protein Name
Probable helicase senataxin
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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