Anti-SETDB1 Antibody Picoband® HRP Conjugated
Product Specifications
Background
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
Synonyms
SETDB1; ESET; KIAA0067; KMT1E; Histone-lysine N-methyltransferase SETDB1; EC 2.1.1.-; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1
Gene Name
SETDB1
Gene ID
9869
UniProt
Q15047
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SETDB1 recombinant protein (Position: E20-E871) . Human SETDB1 shares 92.9% amino acid (aa) sequence identity with mouse SETDB1.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
143 kDa
Gene Name Synonym
SET domain bifurcated histone lysine methyltransferase 1
Protein Name
Histone-lysine N-methyltransferase SETDB1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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