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Anti-SETDB1 Antibody Picoband® Fluoro488 Conjugated

Selected Variant

A00881-3-Fluoro488

Size: 100 µg/Vial

Product Specifications

Background

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Synonyms

SETDB1; ESET; KIAA0067; KMT1E; Histone-lysine N-methyltransferase SETDB1; EC 2.1.1.-; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1

Gene Name

SETDB1

Gene ID

9869

UniProt

Q15047

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SETDB1 recombinant protein (Position: E20-E871) . Human SETDB1 shares 92.9% amino acid (aa) sequence identity with mouse SETDB1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

143 kDa

Applications Notes

6

Gene Name Synonym

SET domain bifurcated histone lysine methyltransferase 1

Protein Name

Histone-lysine N-methyltransferase SETDB1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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